Monoclonal Antibodies

The Monoclonal antibodies (MAbs) collection of IZSLER Biobank contains a selection of MAbs produced within IZSLER Biotechnology Laboratory. They were raised towards viruses of veterinary interest and immunoglobulin isotypes of various animal species and they are regularly used in in-house diagnostic assays.

The IZSLER MAbs have been generated during 30 years of research and development activities finalized to produce strategic tools for both research and diagnostic purposes. They are against a wide spectrum of viruses, bacteria and proteins, mainly of veterinary interest.  The MAbs included in the IZSLER Biobank have been selected as the most relevant and characterized.


Quality controls


Purity of the source

Hybridoma cells producing MAbs are submitted to a double cloning procedure to assure their stability and the clonality of the antibody produced.


Specificity

The monoclonal antibodies expressed by each hybridoma are controlled through a series of immunological assays aimed at identifying and characterising their reactivity profile against the specific antigen.


Quality management system

IZSLER laboratories, that supply biological resources to IBVR, use testing methods performed according to UNI EN ISO/IEC 17025 quality system.

 

Updated to September 2022

 

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