IgG anti immunoglobulins (IgG α-Ig) are reagents that have been used for quite a long time. They have been very useful both in diagnosis and in biomedical research. Initially IgG α-Igs were mainly used in agar gel precipitation, complement fixation reactions or bacterial agglutination. Later on following the development of solid phase, used to passively adsorb large macromolecules, IgGs were “labeled” through the conjugation with different molecules, all capable of releasing some specific signals with high efficiency. Just as an example, IgGs were conjugated with radioisotopes (Radioimmunoassay), fluorophores such as Fluorescein (FITC - immunofluorescence) or with enzymes like horse radish peroxidase (HRP) (Enzyme - linked – immune assay).
Since around 1970 IgG α-Igs , purified and conjugated, mainly with FITC or HRP, are being produced at IZSLER. The anti - IgGs produced recognize mainly IgGs of the most important zootechnical species (cattle, swine, poultry etc.) but also those of some minor species. Up to date the production has been limited to internal diagnostic and research purposes.
Considering that IgG α-Igs conjugated to enzymes or fluorophores for the main animal species are largely available on the market , the present catalog includes only a limited number of IgG α-Igs which are specific for minor animal species that may be useful for research purposes.
Quality management system
IZSLER laboratories, that supply biological resources to IBVR, use testing methods performed according to UNI EN ISO/IEC 17025 quality system.
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BIOBANK infrastructure of IZSLER has the mission of collecting all biological resources submitted to purity and identity controls, stored in different laboratories. It is difficult to get from others biological samples with known characteristics except for those that are obtained from certified Centres.
To cover this gap all biological resources collected at IZSLER biobank have been controlled and characterised by standard protocols to have detailed information on their main features. These data are included in a data base published in this web site.
Biobank infrastructure is made from best of breed technology to preserve all biological resources stored by IZSLER laboratories.
Maria Beatrice Boniotti (Biobank Manager)
Phone: +39 (030) 2290-263 / 273
Fax: +39 (030) 2290-386